It is evident that oral microorganisms have the capacity to respond and adapt to changing environmental conditions. Individual microorganisms are able to sense and process the chemical information from the environment and thereby adjust their phenotypic properties. The term bio lm is used to indicate the presence of a lm of condensed microorganisms on any surface. Bacterial condensations on the walls of infected root canals have been observed suggesting that mechanisms for bio lm formation also exist inside the root canal space. A mature bio lm is a metabolically active community of microorganisms where individuals share duties and bene ts. A growing body of knowledge suggests that organisms in bio lms assume a stronger pathogenic potential than those in a planktonic state. From these aspects, the formation of bio lms carries particular clinical signi cance because not only host defense mechanisms, but also therapeutic efforts including chemical and mechanical anti-microbial treatment measures, have a most dif cult task to deal with organisms that are gathered in a bio lm. Such bacterial aggregations have been thought to be the cause of therapy-resistant apical periodontitis. The aim of this communication is therefore to give an overview of the bio lm concept and to discuss how it may apply to endodontic infections.
Kanaparthy, A. (2012). Biofilms-The Unforgiving Film in Dentistry (Clinical Endodontic Biofilms). Dentistry, 02(07). https://doi.org/10.4172/2161-1122.1000145