A series of pyrido[2,3-d]pyrimidine derivatives were synthesized by the three-component reaction of aromatic aldehyde, malononitrile and 6-amino-4-hydroxy-2-mercaptopyrimidine catalyzed by sodium lauryl sulfate (SDS) in aqueous media. It was interesting that further aromatization took place automatically. This method provides several advantages such as easier work-up, milder reaction conditions and environmental friendly.
Mendeley helps you to discover research relevant for your work.
CITATION STYLE
Li, S. H., Shen, Y. H., Gao, N., & Li, J. T. (2010). One-pot synthesis of some new pyrido[2,3-d]pyrimidine derivatives catalyzed by sodium lauryl sulfate in aqueous media. E-Journal of Chemistry, 7(3), 779–784. https://doi.org/10.1155/2010/230707