Coexistence of human immunodeficiency virus, active pulmonary tuberculosis, and aspergilloma: A rare entity

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Abstract

Tuberculosis (TB) constitutes a significant burden of infectious diseases worldwide. TB and human immunodeficiency virus (HIV) coinfection potentiate each other, which has a negative impact on the disease progression. Aspergillus colonizing a preexisting parenchymal tubercular cavity is referred to as aspergilloma. Aspergilloma occurring in a patient with active TB is unusual. We report the case of a 50-year-old male who presented to us with complaints of cough and recurrent hemoptysis for 3 months. Clinical and radiological examination revealed right upper lobe aspergilloma. A right upper lobectomy was done and a histopathological examination showed evidence of active TB. The patient was started on antitubercular therapy (ATT) followed by antiretroviral therapy (ART). The presence of active TB should not be overlooked in a patient with aspergilloma, especially in immune-compromised individuals such as people living with HIV, as definitive treatment with surgical resection, and ATT along with ART has better outcomes.

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APA

Leo, S., Mulkoju, R., Rajaram, M., & Srinivas, B. H. (2022). Coexistence of human immunodeficiency virus, active pulmonary tuberculosis, and aspergilloma: A rare entity. International Journal of Mycobacteriology, 11(4), 460–462. https://doi.org/10.4103/ijmy.ijmy_164_22

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