Biotransformation of paclitaxel by cell suspension cultures of Marchantia polymorpha

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Abstract

Biotransformation of paclitaxel by cell suspension cultures of Marchantia polymorpha was studied and it was found that liverwort cultures convert paclitaxel to 7-epi-paclitaxel in good yield and regioselectively hydrolyses the ester group at the 10 - position of paclitaxel.

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Sanada, K., Kawaguchi, A., Furuya, T., & Hamada, H. (2000). Biotransformation of paclitaxel by cell suspension cultures of Marchantia polymorpha. Plant Biotechnology, 17(4), 321–323. https://doi.org/10.5511/plantbiotechnology.17.321

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