IRF4-/-Vh11 mice: A novel mouse model of CLL

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Abstract

In this issue of Blood, Shukla and colleagues identify IRF4 -/-Vh11 mice, which develop spontaneous chronic lymphocytic leukemia (CLL) with 100% penetrance within 10 months as a novel mouse model of CLL, providing a new tool for investigating the pathogenesis of CLL and evaluating therapeutic agents. © 2013 by The American Society of Hematology.

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Zhong, Y., & Byrd, J. C. (2013, October 17). IRF4-/-Vh11 mice: A novel mouse model of CLL. Blood. American Society of Hematology. https://doi.org/10.1182/blood-2013-08-521120

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