7-methoxypyrrolo[1,2-a]quinolines via quinolinium N-ylides

Abstract

The pyrrolo[1,2-a]quinoline derivatives 4 and 6 were obtained by 1,3-dipolar cycloaddition of the quinolinium N-ylides in a one-pot three-component reaction under the assistance of the solvent which acts as both reaction medium and HBr scavenger. The one-pot three-component reaction could not be extended to compounds 8a-c which were obtained in two steps. The compounds were characterized by NMR and the cycloadduct 4e was investigated by X-ray analysis.