The Cardioprotective Properties of Pulses and the Molecular Mechanisms of Their Action

Abstract

Legumes and their seeds (pulses) have various nutritional and health benefits and form an important part of a healthy diet. The present work reviews recent studies from the literature concerning the cardioprotective properties of legumes, particularly pulses, and summarizes their molecular basis. The literature was gathered from electronic databases, including ScienceDirect, PubMed, SCOPUS, Web of Knowledge, Sci Finder, and Web of Science, using the following terms: “legume seeds”, “pulses”, “beans”, “peas”, “broad beans”, “chickpea”, “lentils”, “cardiovascular system”, and “cardiovascular disease”, and their combinations. The abstracts of any identified articles were initially analyzed to confirm whether they met the inclusion criteria. Pulses may reduce the risk of cardiovascular diseases (CVDs) by various mechanisms, including altering plasma lipid composition (especially lowering total and LDL cholesterol), increasing satiety, reducing inflammation, and decreasing oxidative stress and blood pressure. It is, however, unclear whether pulses maintain their cardioprotective properties after processing, and more research is needed in this area.