Relation between serum uric acid and diabetes type II

Abstract

Incidence of diabetes mellitus type 2 has been increasing worldwide, making the disease of extreme importance. Several reports have suggested a possible association between serum levels of uric acid (SUA) and higher incidence of diabetes mellitus type 2. On a biological basis, uric acid can negatively affect insulin resistance in animals. This occurs due to the inhibition of nitric oxide which is crucial to achieve glucose uptake. In this study, we aim to: report on previous literature on relation between serum uric acid and diabetes type II in Saudi and prevalence of association between them. PubMed database and EBSCO Information Services were used for articles selection. All relevant articles to our review with the topics regarding the relation between serum uric acid and diabetes type II, and other articles have been used. We excluded other articles, which are not related to this field. The data will be extracted according to specific form in which it is going to be reviewed by the group members. In this meta-analysis we found that SUA levels positively correlate with diabetes mellitus type 2. Future studies should try to determine the reliability of using SUA levels to predict diabetes mellitus type 2 and improve prevention.