False-negative hepatitis B virus (HBV) surface antigen in a vaccinated dialysis patient with a high level of HBV DNA in the United States

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Abstract

Screening with hepatitis B surface antigen (HBsAg) is highly recommended for at-risk individuals. Mutations in the HBsAg can result in an inability to detect the virus during routine screening. We describe a hemodialysis patient found to have high levels of hepatitis B virus (HBV) DNA and HBV antibody but negative HBsAg on two routine assays. Copyright © 2012, American Society for Microbiology.

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Foy, M. C., Thio, C. L., Hwang, H. S., Saulynas, M., Hamilton, J. P., Fine, D. M., & Atta, M. G. (2012). False-negative hepatitis B virus (HBV) surface antigen in a vaccinated dialysis patient with a high level of HBV DNA in the United States. Clinical and Vaccine Immunology, 19(5), 820–822. https://doi.org/10.1128/CVI.05696-11

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