Synthesis of 5,8-Dihydroxy-3,4-dihydrocarbostyril

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Abstract

5,8-Dihydroxy-3,4-dihydrocarbostyril, a key intermediate for the synthesis of β1-selective 8-acetonyloxy-5-[3-(3,4-dimethoxyphenethylamino)-2-hydroxypropoxy]-3, 4-dihydrocarbostyril hydrochloride (opc-1427) was prepared from 2,5-dimethoxyaniline. © 1981, The Pharmaceutical Society of Japan. All rights reserved.

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Tominaga, M., Yo, E., Osaki, M., Manabe, Y., & Nakagawa, K. (1981). Synthesis of 5,8-Dihydroxy-3,4-dihydrocarbostyril. Chemical and Pharmaceutical Bulletin, 29(8), 2161–2165. https://doi.org/10.1248/cpb.29.2161

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