PLINK is a versatile program which supports data management, quality control, and common statistical computations on matrices of genomic variant calls, in a computationally efficient manner. In population genomics, it is frequently used to take care of the “basics,” so they do not need to be reimplemented when a new type of analysis needs to be performed on such a matrix. I describe several of these basic operations, and discuss uses and pitfalls.
CITATION STYLE
Chang, C. C. (2020). Data management and summary statistics with PLINK. In Methods in Molecular Biology (Vol. 2090, pp. 49–65). Humana Press Inc. https://doi.org/10.1007/978-1-0716-0199-0_3
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