The Influence of ABO Blood Group on Surgical Bleeding in 15,857 Patients

Abstract

Patients with Type O blood were reported to have low concentrations of von Willebrand Factor and to have the potential for massive bleeding. We investigated factors contributing to surgical bleeding on our 10―year anesthetic database using multivariate analysis. We extracted the cases from the database and analyzed with patients, demographic values including blood type. Subclass analysis was performed for typical surgeries, including distal gastrectomy, simple hysterectomy, total hip arthroplasty and Caesarian section. A total of 15,857 cases were examined and age （regression coefficient : －0.63 g/yr） （female : +62 g/sex） , sex , weight （+2.1 g/kg） and length of surgery （＋85 g/hr） were selected as independent factors for predicting surgical blood loss. There was no correlation with blood type even though the amount of bleeding was corrected by the independent variables. We conclude that there are no clinical or practical differences for perioperative blood loss between type O and non―O blood patients.