Neurotherapies and Alzheimer's: A protocol-oriented review

Abstract

Due to recent findings in animal models of Alzheimer's disease (AD), neurotherapy studies are reviewed with a focus on brainwave studies, neurofeedback, and audiovisual stimulation techniques with a goal of finding improvement of cognitive impairment from aging and Alzheimer's disease as well as the possible diagnostic, preventative, and therapeutic use in humans. Some protocols which might offer significant improvements in attention, executive functions, and mood states are identified, specifically for the first stages of the disease. The recent advances in microglia stimulation are also reviewed. In general, the analyzed data of the classical protocols match with the result of the last 15 years of investigation of Alzheimer's disease EEG characteristics.