Pediatric-type FL: Simply different

Abstract

In this issue of Blood, the groups of Louissaint et al1 and Schmidt et al2 report on the genetic landscape of pediatric-type follicular lymphoma (PTFL). Their studies confirm suspicions that PTFL represents a biologically distinct form of lymphoma, with fewer recurrent genetic alterations than typical FL. Because this group of patients has an excellent prognosis, accurate and reliable identification of PTFL is important to minimize the prospect of unnecessary treatment.