SOME COMPOUNDS FROM FLOWER OF WEDELIA TRILOBATA (L.) HITCH. (ASTERACEAE)

Abstract

Wedelia trilobata Hitch. has not much been chemically and biologically studied. From the flower of Wedelia trilobata, ten compounds were isolated: friedelan-3β-ol (or epifriedelanol) (1), erythrodiol (2), 28-hydroxy-3β -tetradecanoyloxyolean-12-ene (or 3β -tetradecanoyloxyerythrodiol) (3), 3β-henicosanoyloxyolean-12-en-28-oic acid (4), 3β-pentadecanoyloxyolean-28(13)-lactone (5), kaura-9(11),16-dien-18-oic acid (or grandiflorenic acid) (6), 2-(3-hydroxy-3,7,11,15- tetramethylhexadecyl)-3,5,6-trimethyl-1,4-dihydroxybenzene (or tocopherolhydroquinone) (7), gramisterol (8), stigmasterol (9) and b-sitosterol 3-O-b-D-glucopyranoside (10). The structures of these compounds were determined through the interpretation of their NMR data and compared with references.