Cytogenetic and molecular genetic investigations

3Citations
Citations of this article
4Readers
Mendeley users who have this article in their library.
Get full text

Abstract

Male infertility and hypogonadism may be caused by a genetic defect, which should be investigated by cytoge-netic or molecular genetic analysis. The main indications for genetic testing in andrology are azoospermia and severe oligozoospermia. In selected cases of hypogonadotropic hypogonadism and Kallmann syndrome, especially those with an evident familial component, mutation screening of the known genes may be indicated. Even if detection of a genetic alteration will not substantially change the treatment, genetic testing should be performed for two reasons: (1) to finalize a causal diagnosis, and (2) to assess the genetic risk for the offspring in case of successful treatment. © 2010 Springer-Verlag Berlin Heidelberg.

Cite

CITATION STYLE

APA

Simoni, M., & Wieacker, P. (2010). Cytogenetic and molecular genetic investigations. In Andrology: Male Reproductive Health and Dysfunction (pp. 119–124). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-540-78355-8_8

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free