Marine Natural Products: XXVII: Distribution of Lanostane-Type Triterpene Oligoglycosides in Ten Kinds of Okinawan Sea Cucumbers

Abstract

Triterpene-oligoglycoside constituents in ten sea cucumber species inhabiting Okinawan coral reefs were investigated. Several antifungal oligoglycosides were isolated from six species [stichlorosides At(15), A2 (16), (17), B1 B2 (18), C1 (19), and C2 (20) from Thelonota ananas (baika-namako in Japanese) and Stichopus hermanni; 15,17, and 19 from Thelonota anax; bivittosides C (13) and D (14) from Bohadschia argus (janome-namako); holothurin A (6) from Holothuria edulis (akamishikiri); and 6 and echinoside A (10) from Bohadschia graeffei (kurote-namako)]. Furthermore, several oligoglycosides were isolated in their desulfated forms from four species [6 and 10 from Holothuria axiologa; holothurin B (4), 6, echinoside B (8), and 10 from Holothuria atra (kuro-namako); 6, 10, and 24-dehydroechinoside A (24) from Holothuria scabra (haneji-namako); and 8, 10, 24-dehydroechinoside B (22), and 24 from Actinopyga mauritiana (kuriiro-namako)]. 24-Dehydroechinoside B (22) is a new lanostane-type triterpene oligoglycoside. © 1991, The Pharmaceutical Society of Japan. All rights reserved.