358 GENDER-RELATED DIFFERENCES IN PATIENT-REPORTED OUTCOMES AFTER ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION - DATA FROM THE SWEDISH NATIONAL REGISTER ON ACL RECONSTRUCTION

  • Ageberg E
  • Forssblad M
  • Herbertsson P
  • et al.
N/ACitations
Citations of this article
10Readers
Mendeley users who have this article in their library.

Abstract

Purpose: Knee joint injury, such as anterior cruciate ligament (ACL) injuries, is the major risk factor for osteoarthritis (OA) development in the young and middle-aged. It is suggested that middle-aged women with or at high risk of OA report worse self-reported outcomes and are at greater risk of worsening over time in patient-reported outcomes than men. It is unclear whether gender-related differences in patient-reported outcomes are present also in people with ACL injury, at high risk of OA. The aim was to study gender-related differences in patient-reported outcomes before and after ACL reconstruction. Methods: Patients undergoing surgical reconstruction of the ACL in Sweden are registered in the Swedish National Register on ACL reconstruction. During 2005 - 2008, 10163 patients (mean age 27 years, SD 9.8, 42% women) with primary reconstruction were registered. 4438 (44%) of these patients (mean age 26 years, SD 9.6, 42 % women) had completed the Knee injury and Osteoarthritis Outcome Score (KOOS) before surgery and were {table presented} included in this study. The KOOS is a patient-relevant questionnaire comprising five subscales; pain, other symptoms, activities in daily living (ADL), function in sport and recreation (sport/rec), and knee-related quality of life (QoL). Each subscale is scored on a 0 (worst) to 100 (best) scale. Possible confounding factors, such as age, associated injuries, activity at injury, and graft type did not influence the results (ANCOVA) and were, therefore, not adjusted for. Independent t-tests were used to study gender-related differences in KOOS before (pre-op), at 1 and 2 years after surgery (post-op), and over time (pre-op vs. 1 year post-op and 1 year vs. 2 years post-op). Results: The mean (SD) for the five KOOS subscales at pre-op (n=4432 to 4438), 1 year (n=3851 to 3861), and 2 years (n=2178 to 2184) post-op, respectively, were: KOOS pain 74 (17), 85 (16), 86 (16); KOOS symptoms 68 (18), 79 (18), 79 (17); KOOS ADL 84 (17), 92 (13), 92 (13); KOOS sport/rec 41 (27), 65 (28), 66 (27); KOOS QoL 33 (18), 61 (25), 62 (24). The mean difference (95% CI) between men and women in KOOS scores ranged between 0.6 (-0.4 to 1.6) for KOOS ADL and 4.7 (3.0 to 6.3) for KOOS sport/rec at pre-op, between -0.1 (-1.0 to 0.7) for KOOS ADL and 2.7 (0.9 to 4.4) for KOOS sport/rec at 1 year post-op, and between -0.1 (-1.1 to 1.0) for KOOS ADL and 4.4 (2.1 to 6.7) for KOOS sport/rec at 2 years post-op, with generally lower scores for the women (Table 1). For changes in KOOS scores over time, the mean difference (95% CI) between men and women ranged between -0.1 (-1.8 to 1.6) for KOOS pain and -3.2 (-5.6 to 0.8) for KOOS QoL at pre-op vs. 1 year post-op, and between 0.0 (-1.4 to 1.5) for KOOS symptoms and 3.2 (0.3 to 6.1) for KOOS sport/rec at 1 year vs. 2 years post-op (Table 1). Conclusions: Women reported statistically significantly worse scores in all KOOS subscales, except for KOOS ADL, than men. However, these gender-related differences were too small to be considered clinically relevant. There were no gender-related differences in improvements in KOOS over time.

Cite

CITATION STYLE

APA

Ageberg, E., Forssblad, M., Herbertsson, P., & Roos, E. M. (2009). 358 GENDER-RELATED DIFFERENCES IN PATIENT-REPORTED OUTCOMES AFTER ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION - DATA FROM THE SWEDISH NATIONAL REGISTER ON ACL RECONSTRUCTION. Osteoarthritis and Cartilage, 17, S189–S190. https://doi.org/10.1016/s1063-4584(09)60380-0

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free