Mortality Among Dengue Infection Patients in Bandung City 2022

Abstract

Background: Dengue infection is caused by the dengue virus. In 2021 in Indonesia, 705 mortalities were due to dengue infection, while in 2022, 1,232 mortalities. The CFR in 2019 was 0.67%, in 2020 it was 0.69%, and in 2021 it was 0.96%. Bandung City is one of the endemic areas. In 2022, found 21 reported mortality, with a CFR of 0.47% in 2020, 0.35% in 2021, and 0.19% in 2022. Risk factors for death due to dengue infection are old age, delay in treatment, platelet count, incidence of DSS, and hematocrit value. Methods: This is a quantitative observational study using a nested case-control research design. Uses secondary data from the Bandung City Health Service. Results: The results of this study confirmed association of mortality with age above 40 years (p-value: 0.008, OR: 6.320), high hematocrit value (p-value: 0.005, OR: 11.111), long gap between onset and diagnosis (p-value: 0.025, OR: 13.833), prolonged hospitalization (p-value: <0.001, OR: 8.125), and incidence of DSS (p-value <0.001, OR: 39.500). Low platelet count (p-value: 0.033, OR: 0.263) found to be protective. Conclusions: Age, hematocrit value, gap between onset and diagnosis, length of hospitalization, and incidence of DSS are risk factors for mortality among dengue infection patients.