Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape

  • Hegde M
  • Mukherjee M
  • Grada Z
  • et al.
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Abstract

The corresponding author recently notified the JCI that the patient data presented in Figure 1B were not correct. Analysis of the correct patient data set does not show a significant difference in CERS6expression in human lung adenocarcinomas with positive invasive growth (definite) compared with those with negligible invasive growth or without invasive growth (focal/none). The Editors have requested an institutional investigation into this matter, and we will inform our readers of the outcome when the investigation is complete.

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Hegde, M., Mukherjee, M., Grada, Z., Pignata, A., Landi, D., Navai, S. A., … Ahmed, N. (2019). Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape. Journal of Clinical Investigation, 129(8), 3464–3464. https://doi.org/10.1172/jci131246

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