A case of sarcomatoid carcinoma of the liver

Abstract

A 65-year-old man was admitted to our hospital because of the liver tumor with approximate diameter of 4 cm. It was difficult to make a qualitative diagnosis although extensive examinations implied a primary hepatic lesion. As a result of targeted biopsy of the lesion, a pathological diagnosis of sarcomatoid carcinoma was suggested, and then surgical resection was performed. The tumor was simple nodular and mainly consisted of spindle cells with remarkable pleomorphism and mitosis in compact and fascicular fashion. Immunohistochemically, the tumor cells were positive for AE1/AE3 and vimentin, confirming the diagnosis of sarcomatoid carcinoma. © 2008 The Japan Society of Hepatology.