In vitro antioxidant and antibacterial activity of Quercetin isolated from Indigofera aspalathoides and Quercetin-Zinc metal complex

Abstract

Plant secondary metabolites play a crucial role in the therapeutic applications due to their non toxic nature. The present study was aimed to explore the antioxidant and antibacterial potential of a natural flavonoid Quercetin isolated from the plant Indigofera aspalathoides and Quercetin-Zinc (Qn-Zn) metal complex. The study results explored that, the both Quercetin and Qn-Zn metal complex displayed a strong free radicals quencher against the DPPH, ABTS and superoxide anion free radicals. In addition to that, it has also possessed antibacterial activity against the gram positive (Staphylococcus aureus, Bacillus Subtilis, Enterococcus faecalis) and gram negative (Escherichia coli, Pseudomonas aeruginosa) human pathogenic bacteria. Moreover, we found that and Qn-Zn metal complex displayed slightly better activity than the Quercetin. Overall, the present findings are demonstrated that, the biological activities of natural flavonoid Quercetin were increased, when it’s combined with Zinc metal complex.