Primary hepatic neuroendocrine tumor: Report of one case

Abstract

Primary hepatic neuroendocrine tumor (PHNET) is extremely rare. In our current case, a 41-year-old female was admitted in the department of breast surgery of our center to undergo the radical resection of right breast cancer 2 weeks ago. The pre-operative examinations did not show any liver space-occupying lesion. She had no carcinoid syndrome. Liver contrast-enhanced MRI showed that the tumor was remarkably enhanced in the arterial phase; an adenoma was considered, although the possibility of malignancy could not be excluded. She had a previous history of high blood pressure for 3 years, and the blood pressure was maintained around 130/80 mmHg by oral medications. She was allergic to penicillin. She underwent right hemihepatectomy in the department of hepatobiliary surgery in our center. Postoperative pathology confirmed that the lesion was a neuroendocrine tumor (NET). Post-operative somatostatin receptor (SSTR) scintigraphy, 18F-FDG, PET/CT, 68Ga-DOTA-TATE PET/CT did not reveal any definite tumor sign in liver or other sites. The patient was diagnosed as PHNET, which was treated by radical resection.