Regulation of neurotransmitter receptor localization is critical for synaptic function and plasticity. In this issue of Neuron, Matsuda and colleagues (. Matsuda et al., 2016) uncover a transsynaptic complex consisting of neurexin-3, C1q-like proteins, and kainate receptors that drives glutamate receptor clustering at hippocampal synapses.
Furlanis, E., & Scheiffele, P. (2016, May 18). Synaptic Ménage à Trois. Neuron. Cell Press. https://doi.org/10.1016/j.neuron.2016.05.007