Impact of smoking on dendritic cells in patients with oral squamous cell carcinoma

0Citations
Citations of this article
4Readers
Mendeley users who have this article in their library.

Abstract

Smoking has been shown to alter innate and adaptive immune responses and is directly associated with the onset of oral squamous cell carcinoma (OSCC). The purpose of this study was to evaluate the effect of cigarette smoke exposure on dendritic cells (DCs) from OSCC patients. CD1a and CD83 antibodies were used to identify in OSCC samples of 24 smokers and 24 non-smokers. Density of DCs was calculated in intra and peritumoral areas. Clinical and microscopic findings were reviewed and analyzed for all patients. Smokers with OSCC had a lower density of intra and peritumoral DCs when compared to non-smokers. Tumors classified as moderately/poorly differentiated had lower peritumoral CD1a+ DCs than well-differentiated tumors DCs in the OSCC.

Cite

CITATION STYLE

APA

Stähelin, H., Francisco, A. L. N., Mariano, F. V., Kowalski, L. P., & Gondak, R. (2021). Impact of smoking on dendritic cells in patients with oral squamous cell carcinoma. Brazilian Oral Research, 35, 1–8. https://doi.org/10.1590/1807-3107BOR-2021.VOL35.0075

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free