Pestalafuranones F-J, five new furanone analogues from the endophytic fungus nigrospora sp. BM-2

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Abstract

Five new 2(5H)-furanone-type derivatives, pestalafuranones F-J (compounds 3-7), together with two known compounds, pestalafuranones A (1) and B (2), were isolated from the ethyl acetate extract from the fermentation broth of the endophytic fungus Nigrospora sp. BM-2 in a hypersaline medium. The structures of these metabolites were elucidated by EIMS, HREIMS and NMR spectroscopic data. Compounds 1-7 exhibited no cytotoxic activities against the MDA-MB-231 and Caski cancer cell lines.

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Zhang, H., Deng, Z., Guo, Z., Tu, X., Wang, J., & Zou, K. (2014). Pestalafuranones F-J, five new furanone analogues from the endophytic fungus nigrospora sp. BM-2. Molecules, 19(1), 819–825. https://doi.org/10.3390/molecules19010819

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