Zinc mediated barbier type allylation of cyclic imides and subsequent coupling reactions with carbon nucleophiles

Abstract

Allylations of N-benzyl and N-methyl cyclic imides were accomplished successfully under mild Barbier type conditions using zinc metal, allyl bromide and catalytic amount of PbBr2. Subsequent coupling reactions with some carbon nucleophiles afforded 1,2- and 1,4-addition products in moderate to high yields.