Abstract
Appearance of autoantibodies to tissue transglutaminase (TGA) is the most reliable biomarker to identify celiac disease autoimmunity. A nonradioactive assay of determination of TGA was newly developed using electrochemiluminescence (ECL) technology. This ECL assay has been demonstrated to be more sensitive than current standard radio-binding assay (RBA) in detecting TGA and can detect TGA earlier among high-risk young children followed from birth.
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Zhao, Z., Gu, Y., Miao, D., Hoffmeyer, E., Liu, Y., & Yu, L. (2019). Determination of autoantibodies to transglutaminase by electrochemiluminescence (ECL) assay. In Methods in Molecular Biology (Vol. 1901, pp. 197–203). Humana Press Inc. https://doi.org/10.1007/978-1-4939-8949-2_16
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