Octocrylene (2-ethylhexyl 2-cyano-3,3-diphenyl-2-propenoate) is present in several sunscreens and is known to work synergistically with UV filters. We prepared eight octocrylene-related compounds to test their photoprotective activities by measuring diffuse transmittance. The compounds had varied photoprotection profiles, with Sun Protection Factors (SPF) ranging from 1 to 5 and UVA Protection Factors (UVAPF) ranging from 1 to 8. Compounds 4, 5, and 7 showed the best protection against UVB sunrays, while compounds 5, 6, and 7 presented the best results for protection from UVA, so compound 7 had the most balanced protection overall. Results for compounds 4, 8, and 9 are reported for the ?rst time in the literature.
CITATION STYLE
Polonini, H. C., Lopes, R. S., Beatriz, A., Gomes, R. S., Silva, A. O., De Lima, R. V., … De Lima, D. P. (2014). Synthesis and evaluation of octocrylene-inspired compounds for Uv-filter activity. Quimica Nova, 37(6), 1004–1009. https://doi.org/10.5935/0100-4042.20140160
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