Glucagon for Adrenergic Refractory Anaphylactic Shockin Patients Taking Beta-Blockers during Coronary Angiography

Abstract

128 Yutaka KOYAMA, et al. ten minutes. Considering the possibility that adrenaline might not be effective for this anaphylactic shock because he had been taking beta-blockers, 1 mg of glucagon was administered intravenously. After a few minutes the blood pressure increased and the symptoms disappeared. A 63-year-old man who underwent PCI for the right coronary artery for angina pectoris two years ago was admitted to our hospital for a re-evaluation after coronary treatment for suspected recurrent chest pain. His medical history included hypertension, hyperlipidemia, and an abdominal aortic aneurysm. He and his family didn't have any allergic history. No adverse events had previously been found in the examination using iodine contrast agents (iomeprol, iopromide, and iopamidol) performed at our hospital. He had also been taking beta-blockers (carvedilol 10 mg/day) for angina for two years. He Fig. 1A 68-year-old man (case 1), with the progression of anaphylactic shock during coronary angiography. The details are shown in the text. DIV, intravenous drip infusion; IV, intravenous infusion; IM, Intramuscular injection; SBP, systolic blood pressure; HR, heart rate; SpO 2 , saturation of pulse oximetry. Fig. 2A 63-year-old man (case 2), with the progression of anaphylactic shock during coronary angiography. The details are shown in the text. DIV, intravenous drip infusion; IV, intravenous infusion; IM, Intramuscular injection; SBP, systolic blood pressure; HR, heart rate; SpO 2 , saturation of pulse oximetry