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ADP-ribosylation of p21(ras) and related proteins by Pseudomonas aeruginosa exoenzyme S

Infection and Immunity (1991) 59(11) 4259-4262
DOI: 10.1128/iai.59.11.4259-4262.1991
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Abstract

Pseudomonas aeruginosa exoenzyme S ADP-ribosylates p21(ras) and several related proteins. ADP-ribosylation of p21(ras) does not alter interactions with guanine nucleotides. The ras-related GTP-binding proteins, including Rab3, Rab4, Ral, Rap1A, and Rap2, are also substrates; given these results, we propose a model for the role of exoenzyme S in pathogenesis.

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Coburn, J., & Gill, D. M. (1991). ADP-ribosylation of p21(ras) and related proteins by Pseudomonas aeruginosa exoenzyme S. Infection and Immunity, 59(11), 4259–4262. https://doi.org/10.1128/iai.59.11.4259-4262.1991

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