OP03 Efficacy and safety of the oral selective sphingosine-1-phosphate-1 receptor modulator VTX002 in moderately to severely active Ulcerative Colitis: results from a randomised, double-blind, placebo-controlled, phase 2 trial

  • Sands B
  • Panaccione R
  • D'Haens G
  • et al.
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Abstract

citation ID: jjad212.0003 OP03 Efficacy and safety of the oral selective sphingosine-1-phosphate-1 receptor modulator VTX002 in moderately to severely active Ulcerative Colitis: results from a randomised, double-blind, placebo-controlled, phase 2 trial Background: VTX002 is a novel oral selective sphingosine-1-phosphate-1 (S1P1) receptor modulator in development for the treatment of ulcera-tive colitis (UC). The efficacy and safety of VTX002 in patients with ulcerative colitis (UC) was assessed in a phase 2, multicentre, randomised, double-blind, placebo-controlled study (NCT05156125).

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Sands, B. E., Panaccione, R., D’Haens, G., Schreiber, S., DuVall, A., Kierkus, J., … Danese, S. (2024). OP03 Efficacy and safety of the oral selective sphingosine-1-phosphate-1 receptor modulator VTX002 in moderately to severely active Ulcerative Colitis: results from a randomised, double-blind, placebo-controlled, phase 2 trial. Journal of Crohn’s and Colitis, 18(Supplement_1), i4–i5. https://doi.org/10.1093/ecco-jcc/jjad212.0003

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