Generation of a human iPSC line from a patient with Leigh syndrome

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Abstract

Human iPSC line LND554SV.3 was generated from heteroplasmic fibroblasts of a patient with Leigh syndrome carrying a mutation in the MT-ND5 gene (m.13513G. >. A; p.D393N). Reprogramming factors Oct3/4, Sox2, Klf4, and cMyc were delivered using a non-integrative methodology that involves the use of Sendai virus.

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APA

Galera, T., Zurita, F., González-Páramos, C., Moreno-Izquierdo, A., Fraga, M. F., Fernández, A. F., … Gallardo, M. E. (2016). Generation of a human iPSC line from a patient with Leigh syndrome. Stem Cell Research, 16(1), 63–66. https://doi.org/10.1016/j.scr.2015.12.005

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