Genetic analysis of the FBXO48 gene in Chinese Han patients with Parkinson disease

9Citations
Citations of this article
14Readers
Mendeley users who have this article in their library.

Abstract

The F-box only protein 48 gene (FBXO48) is located in 2p13.3, the disease gene locus of Parkinson disease type 3 (PARK3), and it is one of the paralogs of the F-box only protein 7 gene (FBXO7), which is a causative gene of the Parkinson disease type 15 (PARK15; also known as Parkinsonian-pyramidal disease, PPD). To determine whether genetic mutation in the coding region of the FBXO48 gene plays a role in the etiology of PD, we screened DNA samples from 350 Chinese Han patients with PD. No mutation in the coding region of the FBXO48 gene was identified in our PD cohort, suggesting that mutations in the coding region of the FBXO48 gene play little or no role in the development of PD. © 2013 Elsevier Ireland Ltd.

Cite

CITATION STYLE

APA

Xiu, X., Song, Z., Gao, K., Deng, X., Qi, Y., Zhu, A., … Deng, H. (2013). Genetic analysis of the FBXO48 gene in Chinese Han patients with Parkinson disease. Neuroscience Letters, 541, 224–226. https://doi.org/10.1016/j.neulet.2013.02.031

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free