A large family of proteins is entwined with the evolution of terrestrial vertebrates from fishes. Its original function was defence against viruses and mobile DNA elements, but after domestication of the rogue DNA the former enemies co-evolved to form a new, species-specific mechanism of gene regulation. Michael Gross reports.
Gross, M. (2017). How our genome’s foes became its helpers. Current Biology, 27(10), R365–R368. https://doi.org/10.1016/j.cub.2017.04.040