We describe 2 patients with unusual white matter cystic dilations, which could correspond to widening of the perivascular spaces. They underwent morphologic MR imaging with tractography, functional MR imaging (fMRI), and neuropsychological evaluation. fMRI examination showed no functional reorganization of cortical areas. Tractography showed an apparent decrease of white matter tract vectors into the regions of concern. Findings of the neuropsychological examination were normal. It seems that even an extensive cystic dilation of white matter does not deteriorate brain function.
Mathias, J., Koessler, L., Brissart, H., Foscolo, S., Schmitt, E., Bracard, S., … Kremer, S. (2007). Giant cystic widening of Virchow-Robin spaces: An anatomofunctional study. American Journal of Neuroradiology, 28(8), 1523–1525. https://doi.org/10.3174/ajnr.A0622