Glucokinase is located in secretory granules of pancreatic D-cells

Citations of this article
Mendeley users who have this article in their library.


We immunohistochemically examined the distribution of glucokinase in rat pancreatic islets. Glucokinase immunoreactivity under light microscopy was detected in the cytoplasm of somatostatin cells as well as in that of insulin cells. No specific immunoreactivity was detected in glucagon and pancreatic polypeptide cells. In somatostatin cells, glucokinase immunoreactivity was located by electron microscopy exclusively within secretory granules.




Toyoda, Y., Yoshie, S., Fujita, T., Ito, Y., Nonogaki, T., & Miwa, I. (1997). Glucokinase is located in secretory granules of pancreatic D-cells. FEBS Letters, 415(3), 281–284.

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free