Is heart rate variability better than routine vital signs for prehospital identification of major hemorrhage?

4Citations
Citations of this article
51Readers
Mendeley users who have this article in their library.

Abstract

Abstract Objective During initial assessment of trauma patients, metrics of heart rate variability (HRV) have been associated with high-risk clinical conditions. Yet, despite numerous studies, the potential of HRV to improve clinical outcomes remains unclear. Our objective was to evaluate whether HRV metrics provide additional diagnostic information, beyond routine vital signs, for making a specific clinical assessment: identification of hemorrhaging patients who receive packed red blood cell (PRBC) transfusion. Methods Adult prehospital trauma patients were analyzed retrospectively, excluding those who lacked a complete set of reliable vital signs and a clean electrocardiogram for computation of HRV metrics. We also excluded patients who did not survive to admission. The primary outcome was hemorrhagic injury plus different PRBC transfusion volumes. We performed multivariate regression analysis using HRV metrics and routine vital signs to test the hypothesis that HRV metrics could improve the diagnosis of hemorrhagic injury plus PRBC transfusion vs routine vital signs alone. Results As univariate predictors, HRV metrics in a data set of 402 subjects had comparable areas under receiver operating characteristic curves compared with routine vital signs. In multivariate regression models containing routine vital signs, HRV parameters were significant (P <.05) but yielded areas under receiver operating characteristic curves with minimal, nonsignificant improvements (+ 0.00 to + 0.05). Conclusions A novel diagnostic test should improve diagnostic thinking and allow for better decision making in a significant fraction of cases. Our findings do not support that HRV metrics add value over routine vital signs in terms of prehospital identification of hemorrhaging patients who receive PRBC transfusion.

Cite

CITATION STYLE

APA

Edla, S., Reisner, A. T., Liu, J., Convertino, V. A., Carter, R., & Reifman, J. (2015). Is heart rate variability better than routine vital signs for prehospital identification of major hemorrhage? American Journal of Emergency Medicine, 33(2), 254–261. https://doi.org/10.1016/j.ajem.2014.11.046

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free