Gastric inflammation is highly complex biochemical protective response to the cellular tissue injury. Chronic gastritis is associated with the inflammatory cellular infiltrate predominantly consisting of lymphocyte and plasma cells in gastric mucosa. Many evidences suggest that Helicobacter pylori (H. pylori) infection and non steroidal anti- inflammatory drug (NSAID) ingestion are major causative factors. Both are highly implicated in the pathogenesis of gastric mucosal oxidative injury in humans.
M., M. (2013). Helicobacter Pylori Infection and Its Relevant to Chronic Gastritis. In Current Topics in Gastritis - 2012. InTech. https://doi.org/10.5772/52276