High-intensity focused ultrasound for the treatment of fibroadenomata (HIFU-F) study

4Citations
Citations of this article
18Readers
Mendeley users who have this article in their library.

Abstract

BACKGROUND: Breast fibroadenomata (FAD) are the most common benign lesions in women. For palpable lesions, there are currently three standard treatment options: reassurance (with or without follow-up), vacuum-assisted mammotomy (VAM) or surgical excision. High-intensity focused ultrasound (HIFU) ablation has been used in the treatment of FAD. The drawback of HIFU is its prolonged treatment duration. The aim of this trial is to evaluate circumferential HIFU treatment for the effective ablation of FAD with a reduced treatment time. METHODS/DESIGN: Fifty patients (age >/=18 years) will be recruited with symptomatic FAD, visible on ultrasound (US, grade U2 benign). In patients >/=25 years, cytology or histology will be performed to confirm the diagnosis of a FAD. These patients will receive HIFU treatment using the US-guided Echopulse device (Theraclion Ltd., Malakoff, France) under local anaesthesia. An additional 50 patients will be recruited and contacted 6 months after discharge from the breast clinic. These patients will be offered an US scan to determine the change in size of their FAD. This natural change in size will be compared to the decrease in size after HIFU treatment. Secondary outcome measures include post-treatment complications, patient recorded outcome measures, mean treatment time and cost analysis. TRIAL REGISTRATION: Current Controlled Trials: ISRCTN76622747.

Cite

CITATION STYLE

APA

Peek, M. C. L., Ahmed, M., & Douek, M. (2015). High-intensity focused ultrasound for the treatment of fibroadenomata (HIFU-F) study. Journal of Therapeutic Ultrasound, 3(1). https://doi.org/10.1186/s40349-015-0027-6

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free