Our work represents the first case report of polycystic echinococcosis co-infection with HIV, hepatitis C virus (HCV), and hepatitis B virus (HBV). Structural liver alterations were found to be related to parasitic structures and necroinflammatory foci (karyopyknosis, karyorrhexis, and karyolysis), consistent with Echinococcus vogeli. Visceral adipose tissue and intrahepatic triglyceride droplets (macrovesicular and microvesicular steatosis) indicated abnormal fat anabolism, which probably resulted from both viral-induced hepatopathy and drug-related toxicity. In summary, our results suggest that the observed liver abnormalities reflected the coincident exposure to hepatotropic viruses and parasites causing polycystic echinococcosis and were not indicative of opportunistic relationships among these pathogens. © 2013 International Society for Infectious Diseases.
de Almeida, F. B., Corrêa, C. L., de Siqueira, N. G., de Carvalho, N. V. F. M. dos S. C., Rodrigues-Silva, R., de Andrade, A. F. B., & Machado-Silva, J. R. (2013). Histopathological findings of an uncommon co-infection: Echinococcus vogeli, HIV, hepatitis C virus, and hepatitis B virus. International Journal of Infectious Diseases, 17(10). https://doi.org/10.1016/j.ijid.2013.04.002