Homeobox transcription factors exert essential roles in embryogenesis and are thought to govern regenerative cell differentiation. In this issue of Cell, MacLean and colleagues (MacLean et al., 2005) describe a new homeobox gene cluster composed of genes selectively expressed in reproductive tissues. Remarkably, the cluster is on the X chromosome, and the genes display a colinear pattern of expression.
Hogeveen, K. N., & Sassone-Corsi, P. (2005, February 11). Homeobox galore: When reproduction goes RHOX and roll. Cell. Cell Press. https://doi.org/10.1016/j.cell.2004.12.028