HPV infection and cervical neoplasia: associated risk factors

  • Alves Ribeiro A
  • Cecília Costa M
  • Ribeiro Figueiredo Alves R
  • et al.
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Abstract

Background: Behavioral risks such as age at first sexual intercourse, number of sexual partners and partner's sexual behavior are associated with an increased risk of HPV infection, persistence of the infection and the development of neoplastic precursor lesions. The objective of this study was to evaluate the risk factors associated with HPV positivity and with a diagnosis of cervical neoplasia in women referred with an abnormal cervical smear. Methods: This study evaluated a series of 198 women referred with an abnormal cervical smear. Risk factors for HPV infection were investigated using a questionnaire. All cervical specimens were tested for 27 HPV genotypes using the Roche polymerase chain reaction reverse line blot assay.

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Alves Ribeiro, A., Cecília Costa, M., Ribeiro Figueiredo Alves, R., Lina Villa, L., Aparecida Saddi, V., Aparecida dos Santos Carneiro, M., … Helena Rabelo-Santos, S. (2015). HPV infection and cervical neoplasia: associated risk factors. Infectious Agents and Cancer, 10(16). https://doi.org/10.1186/s13027-015-0011-3

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