Human somatic cell nuclear transfer (SCNT) holds great potential in regenerative medicine; however, its applicability has been limited by great variability in reprogramming efficiencies. A new study in this issue of Cell Stem Cell reports a simple way to expand human SCNT to hard-to-reprogram oocytes (Chung et al., 2015).
Deglincerti, A., & Brivanlou, A. H. (2015, December 3). Human SCNT Gets a Boost from Histone Demethylation. Cell Stem Cell. Cell Press. https://doi.org/10.1016/j.stem.2015.11.014