Hyperdense middle cerebral artery sign

Citations of this article
Mendeley users who have this article in their library.


The early CT finding of an hyperdensity of a portion of the middle cerebral artery Hyperdense Middle Cerebral Artery Sign (HMCAS), in patients with supratentorial stroke, is often indicative of an embolic occlusion. Aim of this study was to verify the incidence and reliability of the HMCAS and its possible correlation with early CT findings and with the extent of late brain damage. We studied 36 patients presenting with symptoms of stroke in the MCA territory, by means of CT and angiography performed respectively within 4 and 6 hours. Follow-up CT scans were then obtained after one week and three months from the ischemic event. The HMCAS was present in 50{%} of our patients and in this group it always correlated positively with the angiographic finding of occlusion. The same group presented a high incidence of erly CT hypodensity (88{%}). Finally the presence of HMCAS might be considered a negative prognostic sign for the development of extensive brain damage.




Kenmuir, C., Totoraitis, R. V., Jovin, T., & Jadhav, A. (2014). Hyperdense middle cerebral artery sign. Practical Neurology. BMJ Publishing Group. https://doi.org/10.1136/practneurol-2013-000672

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free