Heart disease, stroke, and renal failure are leading causes of death with hypertension being the predominant risk factor. Extensive evidence from randomized controlled trials has clearly demonstrated benefit of antihypertensive treatment and blood pressure reduction in reducing cardiovascular events in individuals with hypertension. Accordingly effective blood pressure control is essential to prevent the adverse sequelae of hypertension. Although modern drugs have the capacity to reduce blood pressure in almost every patient with hypertension, the actual blood pressure thresholds at which treatment should be initiated and the target levels at which blood pressure should be maintained still remain a topic of much discussion and debate.
Touyz, R. M., & Dominiczak, A. F. (2016, April 1). Hypertension guidelines: Is it time to reappraise blood pressure thresholds and targets? Hypertension. Lippincott Williams and Wilkins. https://doi.org/10.1161/HYPERTENSIONAHA.116.07090