Hypophyseal triplication: Case report and embryologic considerations

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Hypophyseal triplication is malformation that has not been described previously. We present a child with midline abnormalities who underwent epignathus excision at birth. Brain MR imaging revealed 2 paired lateral pituitary glands and an oval midline gland, each with an independent stalk, connected to a thickened third ventricle floor. Because malformations represent a failure in embryogenesis, this case may provide interesting clues on the normal development of the hypophysis.




Manara, R., Citton, V., Rossetto, M., Padoan, A., & D’Avella, D. (2009). Hypophyseal triplication: Case report and embryologic considerations. American Journal of Neuroradiology, 30(7), 1328–1329. https://doi.org/10.3174/ajnr.A1520

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