Implications and management of anemia in cardiac surgery: Current state of knowledge

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Abstract

Decreasing oxygen delivery during and after cardiopulmo- nary bypass (CPB) can adversely affect patient outcomes. Balancing morbidities associated with anemia, red blood cell (RBC) transfusion, pharmaceuticals to prevent fibrino- lysis, and reoperations for bleeding poses a dilemma. One would optimally balance these factors to minimize patient risk. Uncertainty in defining an optimal transfusion thresh- old, a trigger for reoperation, and a strategy for use of phar- maceuticals is evidenced by the considerable variability in clinical practice worldwide.1,2 Therefore, to gain insight to inform surgical practice, we have brought together current knowledge of the association of preoperative anemia, intraoperative anemia, blood transfusion, and measures to address blood loss with adverse outcomes after cardiac surgery. PREOPERATIVE

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Loor, G., Koch, C. G., Sabik, J. F., Li, L., & Blackstone, E. H. (2012, September). Implications and management of anemia in cardiac surgery: Current state of knowledge. Journal of Thoracic and Cardiovascular Surgery. https://doi.org/10.1016/j.jtcvs.2012.04.014

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