Improving the reliability of manual and automated methods for hippocampal and amygdala volume measurements

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Abstract

Comments on an article by Morey et al. (see record [rid]2009-22051-023[/rid]). The paper is informative and timely as it tackles the issue of volume estimation of the hippocampus and amygdala which have been implicated in studies on the structural substrates of human brain gray matter development and aging cognition and disease. Morey et al. did not provide basic relevant demographics such as gender, handedness and age range, mean and standard deviation of the 20 controls. The authors did not consider two recent and relevant Neuroimage publications that tabulated the hippocampus volumetry manually versus the values obtained using other methods. It would have been interesting if Morey et al. had correlated the systematic bias with respect to the manual delineation in the FreeSurfer-estimated hippocampus volume with the volume of the hippocampus in the anatomical atlas used by FreeSurfer itself. (PsycINFO Database Record (c) 2016 APA, all rights reserved)

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Hasan, K. M., & Pedraza, O. (2009, November 15). Improving the reliability of manual and automated methods for hippocampal and amygdala volume measurements. NeuroImage. Academic Press Inc. https://doi.org/10.1016/j.neuroimage.2009.05.004

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