Objective: To explore the neural pathophysiology of postpartum depression through analyzing fMRI regional homogeneity in postpartum depressed mothers during resting state. Methods: 10 depressed mothers and 11 healthy mothers were recruited and underwent functional MRI scanning during resting state. Results: Compared with healthy mothers, the depressed mothers showed significantly increased posterior cingulate, medial frontal and decreased temporal gyrus regional homogeneity.Conclusions :The results suggest that abnormal neural activities existed in depressed mothers and which may play an important role in psychopathology of postpartum depression. © 2011 Published by Elsevier Ltd.
Wang, X. J., Wang, J., Liu, Z. H., Ming, Y., & Zhang, S. W. (2011). Increased posterior cingulate, medial frontal and decreased temporal regional homogeneity in depressed mothers. A resting-state functional magnetic resonance study. In Procedia Environmental Sciences (Vol. 8, pp. 737–743). Elsevier B.V. https://doi.org/10.1016/j.proenv.2011.10.112